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1.
A selective antibiotic for Lyme disease.
Cell
; 184(21): 5405-5418.e16, 2021 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34619078
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2.
Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors.
Proc Natl Acad Sci U S A
; 119(30): e2113963119, 2022 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35858440
3.
Nonadditive functional interactions between ligand-binding sites of the multidrug efflux pump AdeB from Acinetobacter baumannii.
J Bacteriol
; 206(1): e0021723, 2024 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37850798
4.
Insights into substrate transport and water permeation in the mycobacterial transporter MmpL3.
Biophys J
; 122(11): 2342-2352, 2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36926696
5.
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics.
Antimicrob Agents Chemother
; 67(2): e0137722, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36715507
6.
Identification and structure-activity relationships for a series of N, N-disubstituted 2-aminobenzothiazoles as potent inhibitors of S. aureus.
Bioorg Med Chem Lett
; 89: 129301, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37094726
7.
Study of SQ109 analogs binding to mycobacterium MmpL3 transporter using MD simulations and alchemical relative binding free energy calculations.
J Comput Aided Mol Des
; 37(5-6): 245-264, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37129848
8.
Introduction: Transporters, Porins, and Efflux Pumps.
Chem Rev
; 121(9): 5095-5097, 2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33975431
9.
Transporters Involved in the Biogenesis and Functionalization of the Mycobacterial Cell Envelope.
Chem Rev
; 121(9): 5124-5157, 2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33170669
10.
The Whole Is Bigger than the Sum of Its Parts: Drug Transport in the Context of Two Membranes with Active Efflux.
Chem Rev
; 121(9): 5597-5631, 2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596653
11.
Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors.
Acc Chem Res
; 54(4): 930-939, 2021 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33539084
12.
Defining new chemical space for drug penetration into Gram-negative bacteria.
Nat Chem Biol
; 16(12): 1293-1302, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199906
13.
Recognition of quinolone antibiotics by the multidrug efflux transporter MexB of Pseudomonas aeruginosa.
Phys Chem Chem Phys
; 24(27): 16566-16575, 2022 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35766032
14.
Lpp positions peptidoglycan at the AcrA-TolC interface in the AcrAB-TolC multidrug efflux pump.
Biophys J
; 120(18): 3973-3982, 2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34411576
15.
Inactivation of AdeABC and AdeIJK efflux pumps elicits specific nonoverlapping transcriptional and phenotypic responses in Acinetobacter baumannii.
Mol Microbiol
; 114(6): 1049-1065, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32858760
16.
Loss of RND-Type Multidrug Efflux Pumps Triggers Iron Starvation and Lipid A Modifications in Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 65(10): e0059221, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34252310
17.
Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria.
J Chem Inf Model
; 60(6): 2838-2847, 2020 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32453589
18.
Identification of Binding Sites for Efflux Pump Inhibitors of the AcrAB-TolC Component AcrA.
Biophys J
; 116(4): 648-658, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30691677
19.
Efflux Pumps of Burkholderia thailandensis Control the Permeability Barrier of the Outer Membrane.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31383661
20.
First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors.
Bioorg Med Chem Lett
; 29(14): 1836-1841, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31104993